Article
Platelet derived growth factor induced tenascin-C transcription is phosphoinositide 3-kinase/Akt-dependent and mediated by Ets family transcription factors.
Journal of cellular physiology - 1 Mar 2006
Jinnin Masatoshi, Ihn Hironobu, Asano Yoshihide, Yamane Kenichi, Trojanowska Maria, Tamaki Kunihiko
Abstract excerpt
Previous studies have identified several cytokines as inducers of tenascin-C (TN-C) expression in various tissue culture systems. However, the signaling pathways of the regulation of TN-C expression are almost unknown. In this study, we clarified the molecular mechanism(s) underlying the regulation of the TN-C gene by platelet derived growth factor (PDGF) in cultured human dermal fibroblasts. PDGF induced the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
