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Article

Translational efficiency of rpoS mRNA from Borrelia burgdorferi: effects of the length and sequence of the mRNA leader region.

Biochemical and biophysical research communications - 29 Mar 2013

Archambault Linda, Linscott Joshua, Swerdlow Nicholas, Boyland Kathleen, Riley Eammon, Schlax Paula

Abstract excerpt

Regulation of the enzootic cycle in Borrelia burgdorferi requires a shift to the RNA polymerase alternative sigma factor, RpoS. We used in vitro and in vivo assays to assess the relative importance of the putative Shine-Dalgarno sequence and its sequestration for the translational efficiency of rpoS. We created mutant leader regions in which we either removed the Shine-Dalgarno sequence, disrupted the secondary...

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Identifiers

PMID: 23454119
DOI: 10.1016/j.bbrc.2013.02.063
PMCID: PMC3616328

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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