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Article

Coenzyme Q10 as Treatment for Statin-Associated Muscle Symptoms-A Good Idea, but….

Advances in nutrition (Bethesda, Md.) - 1 Jul 2018

Zaleski Amanda L, Taylor Beth A, Thompson Paul D

Abstract excerpt

3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) are extremely well tolerated but are associated with a range of mild-to-moderate statin-associated muscle symptoms (SAMS). Estimates of SAMS incidence vary from <1% in industry-funded clinical trials to 10-25% in nonindustry-funded clinical trials and ∼60% in some observational studies. SAMS are important because they result in dose reduction or...

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PMID: 30032220
DOI: 10.1093/advances/nmy010
PMCID: PMC6054172

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Source receipt: pubmed, retrieved 7 Sept 2026.

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