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Copy Number Aberrations of Genes Regulating Normal Thymus Development in Thymic Epithelial Tumors

26 Feb 2013

Abstract excerpt

PURPOSES: To determine whether the deregulation of genes relevant for normal thymus development can contribute to the biology of thymic epithelial tumors (TET). EXPERIMENTAL DESIGN: Using array comparative genomic hybridization, we evaluated the copy number aberrations of genes regulating thymus development. The expression of genes most commonly involved in copy number aberrations was evaluated by...

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PMID: 23444221
DOI: 10.1158/1078-0432.ccr-12-3260

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