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Article

Phenotypic differences in virulence and immune response in closely related clinical isolates of influenza A 2009 H1N1 pandemic viruses in mice.

PloS one - 1 Jan 2013

Camp Jeremy V, Chu Yong-Kyu, Chung Dong-Hoon, McAllister Ryan C, Adcock Robert S, Gerlach Rachael L, Wiemken Timothy L, Peyrani Paula, Ramirez Julio A, Summersgill James T, Jonsson Colleen B

Abstract excerpt

To capture the possible genotypic and phenotypic differences of the 2009 influenza A virus H1N1 pandemic (H1N1pdm) strains circulating in adult hospitalized patients, we isolated and sequenced nine H1N1pdm viruses from patients hospitalized during 2009-2010 with severe influenza pneumonia in Kentucky. Each viral isolate was characterized in mice along with two additional H1N1 pandemic strains and one seasonal...

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Identifiers

PMID: 23441208
DOI: 10.1371/journal.pone.0056602
PMCID: PMC3575477

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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