Article
Characterization in vitro and in vivo of a pandemic H1N1 influenza virus from a fatal case.
PloS one - 1 Jan 2013
Rodriguez Ariel, Falcon Ana, Cuevas Maria Teresa, Pozo Francisco, Guerra Susana, García-Barreno Blanca, Martinez-Orellana Pamela, Pérez-Breña Pilar, Montoya Maria, Melero Jose Antonio, Pizarro Manuel, Ortin Juan, Casas Inmaculada, Nieto Amelia
Abstract excerpt
Pandemic 2009 H1N1 (pH1N1) influenza viruses caused mild symptoms in most infected patients. However, a greater rate of severe disease was observed in healthy young adults and children without co-morbid conditions. Here we tested whether influenza strains displaying differential virulence could be present among circulating pH1N1 viruses. The biological properties and the genotype of viruses isolated from a...
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