Article
Mitochondria as a pharmacological target: magnum overview.
IUBMB life - 1 Mar 2013
Olszewska Anna, Szewczyk Adam
Abstract excerpt
Mitochondria, responsible for energy metabolism within the cell, act as signaling organelles. Mitochondrial dysfunction may lead to cell death and oxidative stress and may disturb calcium metabolism. Additionally, mitochondria play a pivotal role in cardioprotective phenomena and a variety of neurodegenerative disorders ranging from Parkinson's to Alzheimer's disease. Mitochondrial DNA mutations may lead to...
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