Article
The JR blood group system: identification of alleles that alter expression.
Transfusion - 1 Nov 2013
Hue-Roye Kim, Zelinski Teresa, Cobaugh Adam, Lomas-Francis Christine, Miyazaki Toru, Tani Yoshihiko, Westhoff Connie M, Reid Marion E
Abstract excerpt
BACKGROUND: The ABCG2 gene encodes antigens of the JR blood group system. Red blood cells (RBCs) from individuals homozygous for ABCG2 null alleles are nonreactive with polyclonal and monoclonal anti-Jr(a) . However, some RBCs have been defined as Jr(a+(W) /-) or Jr(a-), particularly when tested with polyclonal anti-Jr(a) . In an effort to resolve these apparent serologic ambiguities, the current study was...
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