Article
Defining the Jr(a-) phenotype in the Japanese population.
Transfusion - 1 Feb 2014
Tanaka Mitsunobu, Kamada Ikuko, Takahashi Junko, Kimura Keiko, Matsukura Harumichi, Tani Yoshihiko
Abstract excerpt
BACKGROUND: The Jr(a-) phenotype is rare in European and North American populations but is not so rare in Japanese and other Asian populations. Recently, two groups have established the connection between the Jr(a-) phenotype and the ATP-binding cassette, member G2 (ABCG2) gene and concluded that ABCG2-null alleles encode the Jr(a-) phenotype. In Japanese Red Cross Blood Centers, the Jr(a-) phenotype is found...
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