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Article

The distribution of <i><scp>MLL</scp></i> breakpoints correlates with outcome in infant acute leukaemia

21 Feb 2013

Abstract excerpt

Acute leukaemia in early childhood - and mainly infant leukaemia (IL) - is characterized by acquired genetic alterations, most commonly by the presence of distinct MLL rearrangements (MLL-r). The aim of this study was to investigate possible correlations between clinical features and molecular analyses of a series of 545 childhood leukaemia (≤24 months of age) cases: 385 acute lymphoblastic leukaemia (ALL) and...

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PMID: 23432364
DOI: 10.1111/bjh.12250

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