Article
Phenomewide Association Study of Health Outcomes Associated With the Genetic Correlates of 25 Hydroxyvitamin D Concentration and Vitamin D Binding Protein Concentration.
Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Apr 2024
Kresge Hailey A, Blostein Freida, Goleva Slavina, Albiñana Clara, Revez Joana A, Wray Naomi R, Vilhjálmsson Bjarni J, Zhu Zhihong, McGrath John J, Davis Lea K
Abstract excerpt
While it is known that vitamin D deficiency is associated with adverse bone outcomes, it remains unclear whether low vitamin D status may increase the risk of a wider range of health outcomes. We had the opportunity to explore the association between common genetic variants associated with both 25 hydroxyvitamin D (25OHD) and the vitamin D binding protein (DBP, encoded by the GC gene) with a comprehensive range...
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