Article
Relationships of single nucleotide polymorphisms of monocyte chemoattractant protein 1 and chemokine receptor 2 with susceptibility and clinicopathologic characteristics of neoplasia of uterine cervix in Taiwan women.
Reproductive sciences (Thousand Oaks, Calif.) - 1 Oct 2013
Wu Hsin-Hung, Lee Tsung-Hsien, Tee Yi-Torng, Chen Shiuan-Chih, Yang Shun-Fa, Lee Shu-Kuei, Ko Jiunn-Liang, Wang Po-Hui
Abstract excerpt
Few studies reported the implication of single nucleotide polymorphisms (SNPs) of monocyte chemoattractant protein 1 (MCP-1) and its receptor chemokine receptor 2 (CCR-2) in clinical significance of cancer of uterine cervix. We hypothesized that SNPs of MCP-1 and CCR-2 may affect the expression of these genes and then proteins. Therefore, we investigated the influence of the gene polymorphisms of MCP-1 and CCR-2...
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