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Article

Genetic polymorphisms of epidermal growth factor in relation to risk of hepatocellular carcinoma: two case-control studies.

BMC gastroenterology - 18 Feb 2013

Yuan Jian-Min, Fan Yunhua, Ognjanovic Simona, Wang Renwei, Van Den Berg David, Govindarajan Sugantha, Yu Mimi C

Abstract excerpt

BACKGROUND: Earlier, we reported a highly statistically significant association between T-helper 1 (Th1) and Th2 cytokine genotypes and hepatocellular carcinoma (HCC) risk among natives of southern Guangxi, China, a hyperendemic region for HCC. Epidermal growth factor (EGF) plays a critical role in malignant transformation of hepatocytes and tumor progression. A polymorphism in the EGF gene (61A > G) results in...

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Identifiers

PMID: 23419149
DOI: 10.1186/1471-230X-13-32
PMCID: PMC3621500

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EGF

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Genetic polymorphisms of epidermal growth factor in relation to risk of hepatocellular carcinoma: two case-control studies.PMID 23419149Read ↗

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Association between epidermal growth factor 61A/G polymorphism and hepatocellular carcinoma susceptibility in Chinese patients.Semantic proximity Read ↗

Epidermal growth factor +61 G/A polymorphism and the risk of hepatocellular carcinoma in a Chinese population.Semantic proximity Read ↗

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