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Article

Sequencing approach to analyze the role of quasispecies for classical swine fever.

Virology - 30 Mar 2013

Töpfer Armin, Höper Dirk, Blome Sandra, Beer Martin, Beerenwinkel Niko, Ruggli Nicolas, Leifer Immanuel

Abstract excerpt

Classical swine fever virus (CSFV) is a positive-sense RNA virus with a high degree of genetic variability among isolates. High diversity is also found in virulence, with strains covering the complete spectrum from avirulent to highly virulent. The underlying genetic determinants are far from being understood. Since RNA polymerases of RNA viruses lack any proof-reading activity, different genome variations called...

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PMID: 23415390
DOI: 10.1016/j.virol.2012.11.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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