Article
Androgen receptor may be responsible for gender disparity in gastric cancer.
Medical hypotheses - 1 May 2013
Tian Ye, Wan Han, Lin Yao, Xie Xu, Li ZeYu, Tan Guang
Abstract excerpt
Men are at a higher risk of developing gastric cancer than women. However, the exact mechanisms responsible for the gender differences remain unclear. Recently, a number of epidemiological and genotyping studies have attributed the gender disparity in male-predominant cancers to the disruption of androgen receptor (AR) homeostasis. Moreover, previous data indicated that AR expression is an independent unfavorable...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
