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Article

High prevalence of genetic variants previously associated with Brugada syndrome in new exome data.

Clinical genetics - 1 Nov 2013

Risgaard B, Jabbari R, Refsgaard L, Holst A G, Haunsø S, Sadjadieh A, Winkel B G, Olesen M S, Tfelt-Hansen J

Abstract excerpt

More than 300 variants in 12 genes have been associated with Brugada syndrome (BrS) which has a prevalence ranging between 1:2000 and 1:100,000. Until recently, there has been little knowledge regarding the distribution of genetic variations in the general population. This problem was partly solved, when exome data from the NHLI GO Exome Sequencing Project (ESP) was published. In this study, we aimed to report...

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PMID: 23414114
DOI: 10.1111/cge.12126

Genes

CACNB2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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