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Article

Genetic Analysis of Arrhythmogenic Diseases in the Era of NGS: The Complexity of Clinical Decision-Making in Brugada Syndrome.

PloS one - 1 Jan 2015

Allegue Catarina, Coll Mònica, Mates Jesus, Campuzano Oscar, Iglesias Anna, Sobrino Beatriz, Brion Maria, Amigo Jorge, Carracedo Angel, Brugada Pedro, Brugada Josep, Brugada Ramon

Abstract excerpt

BACKGROUND: The use of next-generation sequencing enables a rapid analysis of many genes associated with sudden cardiac death in diseases like Brugada Syndrome. Genetic variation is identified and associated with 30-35% of cases of Brugada Syndrome, with nearly 20-25% attributable to variants in...

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Source

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Identifiers

PMID: 26230511
DOI: 10.1371/journal.pone.0133037
PMCID: PMC4521779

Genes

AKAP9
ANK2
CASQ2
DSG2
DSP
JUP
KCNJ2
RYR2
CACNB2
CAV3
DSC2
HCN4
KCNH2
KCNJ5
KCNQ1
PKP2
SNTA1
TMEM43

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26230511-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Genetic Analysis of Arrhythmogenic Diseases in the Era of NGS: The Complexity of Clinical Decision-Making in Brugada Syndrome.PMID 26230511Read ↗

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