Article
Obesity-susceptibility loci and the tails of the pediatric BMI distribution.
Obesity (Silver Spring, Md.) - 1 Jun 2013
Mitchell Jonathan A, Hakonarson Hakon, Rebbeck Timothy R, Grant Struan F A
Abstract excerpt
OBJECTIVE: To determine whether previously identified adult obesity susceptibility loci were associated uniformly with childhood BMI across the BMI distribution. DESIGN AND METHODS: Children were recruited through the Children's Hospital of Philadelphia (n = 7,225). Associations between the following loci and BMI were assessed using quantile regression: FTO (rs3751812), MC4R (rs12970134), TMEM18 (rs2867125), BDNF...
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