Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variation-optimized treatment benefit of angiotensin-converting enzyme inhibitors in patients with stable coronary artery disease: a 12-year follow-up study.

Pharmacogenetics and genomics - 1 Apr 2013

Lee Jen-Kuang, Wu Cho-Kai, Tsai Chia-Ti, Lin Lian-Yu, Lin Jou-Wei, Chien Kuo-Liong, Hwang Juey-Jen, Lin Chunn-Lee, Tseng Chuen-Den, Chiang Fu-Tien

Abstract excerpt

OBJECTIVES: The objective of this study was to examine the relationship between renin-angiotensin system genotypes and the pharmacogenetics of angiotensin-converting enzyme (ACE) inhibitors in Chinese patients with coronary artery disease (CAD). METHODS: Patients with angiographic CAD were recruited from 1995 to 2003. The baseline characteristics and genetic polymorphisms [ACE gene insertion/deletion (I/D)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiotensin-Converting Enzyme Inhibitors
Share to Coronary Artery Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Follow-Up Studies

Share to Kaplan-Meier Estimate

Share to Peptidyl-Dipeptidase A

Share to Proportional Hazards Models

Share to Receptor, Angiotensin, Type 1

Share to Renin-Angiotensin System

Source

Identifiers

PMID: 23407050
DOI: 10.1097/FPC.0b013e32835a0ffa

Genes

ACE
CAD
AGT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation-optimized treatment benefit of angiotensin-converting enzyme inhibitors in patients with stable coronary artery disease: a 12-year follow-up study.PMID 23407050Read ↗

Pharmacogenetics of angiotensin-converting enzyme inhibitors (ACEI) and angiotensin II receptor blockers (ARB) in cardiovascular diseasesSemantic proximity Read ↗

Angiotensin-converting enzyme single nucleotide polymorphism is a genetic risk factor for cardiovascular disease: a cohort study of hypertensive patients.Semantic proximity Read ↗

Drug-gene interactions in older patients with coronary artery diseaseSemantic proximity Read ↗

Traditional risk factors and angiotensin-converting enzyme insertion/deletion gene polymorphism in coronary artery disease.Semantic proximity Read ↗

Does angiotensin-converting enzyme gene polymorphism affect blood pressure? Findings after 6 years of follow-up in healthy subjects.Semantic proximity Read ↗

Angiotensin-Converting Enzyme Insertion/Deletion Gene Polymorphic Variant as a Marker of Coronary Artery Disease<subtitle>A Meta-analysis</subtitle>Semantic proximity Read ↗

Genetic determinants of treatment benefit of the angiotensin-converting enzyme-inhibitor perindopril in patients with stable coronary artery disease.Semantic proximity Read ↗

A 6-Month Follow-Up Study of the Relation between Apolipoprotein E Gene Polymorphism and Major Adverse Cardiovascular Events in Patients with Acute Coronary Syndrome.Semantic proximity Read ↗

Genetic variation in the renin-angiotensin-aldosterone system is associated with cardiovascular risk factors and early mortality in established coronary heart disease.Semantic proximity Read ↗

Pharmacogenetic Risk Stratification in Angiotensin-Converting Enzyme Inhibitor-Treated Patients with Congestive Heart Failure: A Retrospective Cohort Study.Semantic proximity Read ↗

Renin-angiotensin-aldosterone system polymorphisms and 5-year mortality in survivors of acute myocardial infarction: a report from the Osaka Acute Coronary Insufficiency Study.Semantic proximity Read ↗

Polygenetic regression model of renin-angiotensin system genes and the risk of coronary artery disease in a large angiographic population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.