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Article

Polygenetic regression model of renin-angiotensin system genes and the risk of coronary artery disease in a large angiographic population.

Clinica chimica acta; international journal of clinical chemistry - 18 Mar 2011

Tsai Chia-Ti, Hwang Juey-Jen, Wu Cho-Kai, Lee Jen-Kuang, Tseng Chuen-Den, Wang Yi-Chih, Hsu Kuan-Lih, Lai Ling-Ping, Lin Jiunn-Lee, Chiang Fu-Tien

Abstract excerpt

BACKGROUND: Polygenetic effect has rarely been addressed in the genetic studies of coronary artery disease (CAD). We used the largest and ethnically homogeneous angiographic cohort to analyze multilocus data in renin-angiotensin system genes, and provide an explicit demonstration of gene-gene interactions. METHODS: A total of 1254 consecutive patients who underwent cardiac catheterization (735 with coronary...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21184753
DOI: 10.1016/j.cca.2010.12.017

Genes

ACE
AGT
CAD

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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