Article
Microsatellite tandem repeats are abundant in human promoters and are associated with regulatory elements.
PloS one - 1 Jan 2013
Sawaya Sterling, Bagshaw Andrew, Buschiazzo Emmanuel, Kumar Pankaj, Chowdhury Shantanu, Black Michael A, Gemmell Neil
Abstract excerpt
Tandem repeats are genomic elements that are prone to changes in repeat number and are thus often polymorphic. These sequences are found at a high density at the start of human genes, in the gene's promoter. Increasing empirical evidence suggests that length variation in these tandem repeats can affect gene regulation. One class of tandem repeats, known as microsatellites, rapidly alter in repeat number. Some of...
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