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TRPing up the genome: Tandem repeat polymorphisms as dynamic sources of genetic variability in health and disease.

Discovery medicine - 1 Oct 2010

Hannan Anthony J

Abstract excerpt

Repetitive DNA sequences constitute a large fraction of the genomes of humans and other animal species. Tandem repeats are a major class of repetitive DNA and the extent of their polymorphic distributions and functions within the human genome are only beginning to be explored. Tandem repeat polymorphisms (TRPs) provide a unique source of genomic variability and recent evidence suggests they can modulate a range...

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PMID: 21034672

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