Article
A novel method for the analysis of drug-resistant phenotypes of hepatitis B virus.
International journal of molecular medicine - 1 Apr 2013
Qin Bo, He Tingting, Chen Zhijun, Xu Wenying, Pan Guoshao, Tu Chunyu
Abstract excerpt
Chronic hepatitis B virus (CHB) infection is a major cause of cirrhosis and hepatocellular carcinoma. Nucleoside analogs (NAs) are popularly used to treat chronic hepatitis B virus (HBV) infections; however, the anti-HBV effect is attenuated by drug-resistant viral mutations selected during long-term antiviral therapy. The timely analysis of drug-resistance mutations is essential in order to adjust treatment...
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