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Article

Epiplakin modifies the motility of the HeLa cells and accumulates at the outer surfaces of 3-D cell clusters.

The Journal of dermatology - 1 Apr 2013

Shimada Hiromitsu, Nambu-Niibori Akiko, Wilson-Morifuji Masayo, Mizuguchi Souhei, Araki Norie, Sumiyoshi Hideaki, Sato Mitsuru, Mezaki Yoshihiro, Senoo Haruki, Ishikawa Kazushi, Hatano Yutaka, Okamoto Osamu, Fujiwara Sakuhei

Abstract excerpt

Elimination of epiplakin (EPPK) by gene targeting in mice results in acceleration of keratinocyte migration during wound healing, suggesting that epithelial cellular EPPK may be important for the regulation of cellular motility. To study the function of EPPK, we developed EPPK knock-down (KD) and EPPK-overexpressing HeLa cells and analyzed cellular phenotypes and motility by fluorescence/differential interference...

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Identifiers

PMID: 23398049
DOI: 10.1111/1346-8138.12076

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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