Article
Genome-wide association study identifies three loci associated with melanoma risk.
Nature genetics - 1 Aug 2009
Bishop D Timothy, Demenais Florence, Iles Mark M, Harland Mark, Taylor John C, Corda Eve, Randerson-Moor Juliette, Aitken Joanne F, Avril Marie-Francoise, Azizi Esther, Bakker Bert, Bianchi-Scarrà Giovanna, Bressac-de Paillerets Brigitte, Calista Donato, Cannon-Albright Lisa A, Chin-A-Woeng Thomas, Debniak Tadeusz, Galore-Haskel Gilli, Ghiorzo Paola, Gut Ivo, Hansson Johan, Hocevar Marko, Höiom Veronica, Hopper John L, Ingvar Christian, Kanetsky Peter A, Kefford Richard F, Landi Maria Teresa, Lang Julie, Lubiński Jan, Mackie Rona, Malvehy Josep, Mann Graham J, Martin Nicholas G, Montgomery Grant W, van Nieuwpoort Frans A, Novakovic Srdjan, Olsson Håkan, Puig Susana, Weiss Marjan, van Workum Wilbert, Zelenika Diana, Brown Kevin M, Goldstein Alisa M, Gillanders Elizabeth M, Boland Anne, Galan Pilar, Elder David E, Gruis Nelleke A, Hayward Nicholas K, Lathrop G Mark, Barrett Jennifer H, Bishop Julia A Newton
Abstract excerpt
We report a genome-wide association study of melanoma conducted by the GenoMEL consortium based on 317K tagging SNPs for 1,650 selected cases and 4,336 controls, with replication in an additional two cohorts (1,149 selected cases and 964 controls from GenoMEL, and a population-based case-control study in Leeds of 1,163 cases and 903 controls). The genome-wide screen identified five loci with genotyped or imputed...
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