Article
Pulmonary manifestations of chronic granulomatous disease.
Expert review of clinical immunology - 1 Feb 2013
Mahdaviani Seyed Alireza, Mohajerani Seyed Amir, Rezaei Nima, Casanova Jean-Laurent, Mansouri Seyed Davood, Velayati Ali Akbar
Abstract excerpt
Chronic granulomatous disease (CGD) is an inherited disorder, characterized by defects in superoxide-generating NADPH oxidase of phagocytes. The genetic defects in CGD induce failure to activate the respiratory burst in the phagocytes, leading to severe recurrent infections and unexplained prolon...
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