Article
The transcriptome of lae1 mutants of Trichoderma reesei cultivated at constant growth rates reveals new targets of LAE1 function.
BMC genomics - 9 Jun 2014
Fekete Erzsébet, Karaffa Levente, Karimi Aghcheh Razieh, Németh Zoltán, Fekete Eva, Orosz Anita, Paholcsek Melinda, Stágel Anikó, Kubicek Christian P
Abstract excerpt
BACKGROUND: The putative methyltransferase LaeA is a global regulator that affects the expression of multiple secondary metabolite gene clusters in several fungi. In Trichoderma reesei, its ortholog LAE1 appears to predominantly regulate genes involved in increasing competitive fitness in its environment, including expression of cellulases and polysaccharide hydrolases. A drawback in all studies related to...
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