Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lower incidence of nonsyndromic cleft lip with or without cleft palate in females: is homocysteine a factor?

Journal of biosciences - 1 Mar 2013

Kumari Priyanka, Ali Akhtar, Sukla Krishna K, Singh Subodh K, Raman Rajiva

Abstract excerpt

In India, as in other parts of the world, nonsyndromic cleft lip with or without cleft palate (NSCL +/- P) is a highly prevalent birth defect, its incidence in males being twice that in females. A case-control association study has been carried out with respect to homocysteine level and MTHFR C677T, A1298C and SLC19A1 (RFC1) G80A genotypes from an eastern Indian cohort to investigate whether Hcy and other...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cleft Lip
Share to Cleft Palate
Share to Homocysteine

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Incidence

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Reduced Folate Carrier Protein

Share to Sex Factors

Source

Identifiers

PMID: 23385809
DOI: 10.1007/s12038-013-9298-7

Genes

MTHFR
RFC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lower incidence of nonsyndromic cleft lip with or without cleft palate in females: is homocysteine a factor?PMID 23385809Read ↗

Association of Fetal MTHFR 677C > T Polymorphism with Non-Syndromic Cleft Lip with or without Palate Risk: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase C677T polymorphism is not associated with the risk of nonsyndromic cleft lip/palate: An updated meta-analysis.Semantic proximity Read ↗

Genetic and non‐genetic factors that increase the risk of non‐syndromic cleft lip and/or palate developmentSemantic proximity Read ↗

Increased susceptibility for nonsyndromic cleft lip with or without cleft palate by SLC19A1 80G>A genetic variation.Semantic proximity Read ↗

Significant association of MTHFD1 1958G>A single nucleotide polymorphism with nonsyndromic cleft lip and palate in Indian population.Semantic proximity Read ↗

Variable contribution of the MTHFR C677T polymorphism to non-syndromic cleft lip and palate risk in China.Semantic proximity Read ↗

Maternal MTR genotype contributes to the risk of non-syndromic cleft lip and palate in the Polish population.Semantic proximity Read ↗

A meta-analysis and meta-regression of association between MTHFR A1298C polymorphism and nonsyndromic cleft lip/palate risk: An evaluation based on five genetic models.Semantic proximity Read ↗

MTHFR C677T and A1298C polymorphisms and risk of nonsyndromic orofacial clefts in a south Indian population.Semantic proximity Read ↗

MTHFR 677TT alone and IRF6 820GG together with MTHFR 677CT, but not MTHFR A1298C, are risks for nonsyndromic cleft lip with or without cleft palate in an Indian population.Semantic proximity Read ↗

MTR, MTRR, and MTHFR Gene Polymorphisms and Susceptibility to Nonsyndromic Cleft Lip With or Without Cleft Palate.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and nonsyndromic orofacial clefts susceptibility in a southern Chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.