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Article

ATG proteins mediate efferocytosis and suppress inflammation in mammary involution.

Autophagy - 1 Apr 2013

Teplova Irina, Lozy Fred, Price Sandy, Singh Sukhwinder, Barnard Nicola, Cardiff Robert D, Birge Raymond B, Karantza Vassiliki

Abstract excerpt

Involution is the process of post-lactational mammary gland regression to quiescence and it involves secretory epithelial cell death, stroma remodeling and gland repopulation by adipocytes. Though reportedly accompanying apoptosis, the role of autophagy in involution has not yet been determined. We now report that autophagy-related (ATG) proteins mediate dead cell clearance and suppress inflammation during...

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Source

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Identifiers

PMID: 23380905
DOI: 10.4161/auto.23164
PMCID: PMC3627664

Genes

ATG7
BECN1
ITGB5
MERTK
RAC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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