Article
Role of autophagy in breast cancer.
Autophagy - 1 Jan 2000
Karantza-Wadsworth Vassiliki, White Eileen
Abstract excerpt
Autophagy is an evolutionarily conserved process of cytoplasm and cellular organelle degradation in lysosomes. Autophagy is a survival pathway required for cellular viability during starvation; however, if it proceeds to completion, autophagy can lead to cell death. In neurons, constitutive autophagy limits accumulation of polyubiquitinated proteins and prevents neuronal degeneration. Therefore, autophagy has...
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