Differences in islet-enriched miRNAs in healthy and glucose intolerant human subjects

Abstract excerpt

Many microRNAs (miRNAs) are known to be cell-type specific and are implicated in development of diseases. We investigated the global expression pattern of miRNAs in human pancreatic islets compared to liver and skeletal muscle, using bead-based technology and quantitative RT-PCR. In addition to the known islet-specific miR-375, we also found enrichment of miR-127-3p, miR-184, miR-195 and miR-493∗ in the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to MicroRNA in disease regulation
• Share to Pancreatic function and diabetes
• Share to RNA modifications and cancer