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Article

Mutation analysis of the SHFM1 gene in breast/ovarian cancer families.

Journal of cancer research and clinical oncology - 1 Mar 2013

Bonache Sandra, de la Hoya Miguel, Gutierrez-Enriquez Sara, Tenés Anna, Masas Miriam, Balmaña Judith, Diez Orland

Abstract excerpt

PURPOSE: About 5-10 % of breast cancer is due to inherited disease predisposition. Currently known susceptibility genes such as BRCA1 and BRCA2 explain less than 25 % of familial aggregation of breast cancer, which suggests the involvement of additional genetic susceptibility. The SHFM1 [split hand/foot malformation (ectrodactyly) type 1] gene plays an important role in the regulation of gene transcription and...

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Source

Identifiers

PMID: 23371468
DOI: 10.1007/s00432-013-1385-5

Genes

BRCA2
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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