Article

Novel variants of TP63 identified in Chinese families with split-hand/foot malformation

2026-05-26

Abstract excerpt

<title>Abstract</title> <p> Objective Split-hand/foot malformation (SHFM) is a group of congenital birth defects affecting the hands and feet, significantly impairing patients quality of life. The <italic>TP63</italic> gene encodes the p63 protein, heterozygous <italic>TP63</italic> variants can caused SHFM. The aim of this study was to identify <italic>TP63</italic> gene variants in three Chinese familie...

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Literature Corpus work: d31a1284-b983-5cf6-ad32-97263d540ae1
DOI: 10.21203/rs.3.rs-9446031/v1

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