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Article

Fine mapping of the split-hand/split-foot locus (SHFM3) at 10q24: evidence for anticipation and segregation distortion.

American journal of human genetics - 1 Jun 1999

Ozen R S, Baysal B E, Devlin B, Farr J E, Gorry M, Ehrlich G D, Richard C W

Abstract excerpt

Split-hand/split-foot malformation (SHFM, ectrodactyly, or lobster-claw deformity) is a human limb malformation characterized by aberrant development of central digital rays with absence of fingers and toes, a deep median cleft, and fusion of remaining digits. SHFM is clinically heterogeneous, presenting both in an isolated form and in combination with additional abnormalities affecting the tibia and/or other...

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Identifiers

PMID: 10330351
DOI: 10.1086/302403
PMCID: PMC1377907

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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