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Article

TWIST1, A novel androgen-regulated gene, is a target for NKX3-1 in prostate cancer cells

1 Jan 2013

Abstract excerpt

BACKGROUND: TWIST1 plays a key role in EMT-mediated tumor invasion and metastasis. Since bone metastasis is a hallmark of advanced prostate cancer and is detected in at least 85% of patients who die of this disease, it is of great importance to understand the regulation of the cellular signaling pathways involved in the metastatic process. METHODS: Prostatic cell lines were analyzed using real time RT-PCR,...

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PMID: 23368843
DOI: 10.1186/1475-2867-13-4

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