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Article

STAT3 mediates TGF-β1-induced TWIST1 expression and prostate cancer invasion.

Cancer letters - 9 Aug 2013

Cho Kyung Hwa, Jeong Kang Jin, Shin Shang Cheul, Kang Jaeku, Park Chang Gyo, Lee Hoi Young

Abstract excerpt

TGF-β1 induces epithelial-mesenchymal transition (EMT) to stimulate cancer cell progression, and TWIST1 is a critical regulator of EMT. In the present study, we determined the underlying mechanisms of TGF-β1-induced TWIST1 expression and its effect on prostate cancer cell invasion. TGF-β1 stimula...

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Source

Identifiers

PMID: 23623921
DOI: 10.1016/j.canlet.2013.04.024

Genes

TWIST1
STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23623921-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Research trail→

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STAT3 mediates TGF-β1-induced TWIST1 expression and prostate cancer invasion.PMID 23623921Read ↗

Regulation of Cancer Cell Survival, Migration, and Invasion by Twist: AKT2 Comes to InterplaySemantic proximity Read ↗

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Gamma synuclein is a novel Twist1 target that promotes TGF-β-induced cancer cell migration and invasionSemantic proximity Read ↗

Expression and significance of E-cadherin, N-cadherin, transforming growth factor-β1 and Twist in prostate cancerSemantic proximity Read ↗

Twist1 and AP-1 cooperatively upregulate integrin α5 expression to induce invasion and the epithelial–mesenchymal transitionSemantic proximity Read ↗

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Twist Is Transcriptionally Induced by Activation of STAT3 and Mediates STAT3 Oncogenic FunctionSemantic proximity Read ↗

Twist-related protein 1 promotes transforming growth factor β receptor 1 in keloid fibroblasts via regulating the stability of myocyte enhancer factor 2ASemantic proximity Read ↗

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