Article
HLA-E*0103X is associated with susceptibility to Pemphigus vulgaris.
Experimental dermatology - 1 Feb 2013
Bhanusali Dhaval G, Sachdev Amit, Rahmanian Abootaleb, Gerlach John A, Tong Joo Chaun, Seiffert-Sinha Kristina, Sinha Animesh A
Abstract excerpt
Non-classical human leucocyte antigen-E (HLA-E) mediates natural killer and CD8+ T-cell activity, suggesting a role in the regulation of autoimmunity. HLA-E*0103X/*0103X has been associated with Behcet's disease and HLA-E *0101/*0103X with childhood onset diabetes. We investigated HLA-E allele status in 52 Caucasian and Ashkenazi Jewish Pemphigus vulgaris (PV) patients and 51 healthy controls by restriction...
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