Comparison of Targeted Next‐Generation Sequencing (NGS) and Real‐Time PCR in the Detection of <i>EGFR</i>, <i>KRAS,</i> and <i>BRAF</i> Mutations on Formalin‐Fixed, Paraffin‐Embedded Tumor Material of Non‐Small Cell Lung Carcinoma—Superiority of NGS

Abstract excerpt

The development of tyrosine kinase inhibitor treatments has made it important to test cancer patients for clinically significant gene mutations that influence the benefit of treatment. Targeted next-generation sequencing (NGS) provides a promising method for diagnostic purposes by enabling the simultaneous detection of multiple mutations in various genes in a single test. The aim of our study was to screen EGFR,...

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