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Article

Role of Interleukin 6 in Innate Immunity to Mycobacterium tuberculosis Infection

28 Jan 2013

Abstract excerpt

BACKGROUND: Mycobacterium tuberculosis can grow in the hostile intracellular environment of macrophages by actively evading macrophage-associated antibacterial activities. The stress response factor SigH contributes to this process by modulating β-chemokine and interleukin 6 (Il6) expression. Hence, Il6 is of critical importance for acquired immunity against M. tuberculosis infection. Here, we attempted to better...

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PMID: 23359591
DOI: 10.1093/infdis/jit037

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