Article
Longer HSD11B2 CA-repeat in impaired glucose tolerance and type 2 diabetes.
Endocrine journal - 1 Jan 2013
Mune Tomoatsu, Suwa Tetsuya, Morita Hiroyuki, Isomura Yukinori, Takada Nobuki, Yamamoto Yoritsuna, Hayashi Makoto, Yamakita Noriyoshi, Sasaki Akihiko, Takeda Noriyuki, Takeda Jun, White Perrin C, Kaku Kohei
Abstract excerpt
Type 2 11β-hydroxysteroid dehydrogenase encoded by the HSD11B2 gene converts cortisol to inactive cortisone, and alteration in this enzymatic activity might affect glucose homeostasis by affecting circulating levels or tissue availability of glucocorticoids. We investigated the association of HSD...
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