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Article

Variant screening of the serum amyloid A1 gene and functional study of the p.Gly90Asp variant for its role in atherosclerosis.

Atherosclerosis - 1 Mar 2013

Leow Koon-Yeow, Goh Wilson Wen Bin, Tan Si-Zhen, Lim Jimmy, Ng Kenneth, Oh Vernon Min-Sen, Low Adrian Fatt-Hoe, Heng Chew-Kiat

Abstract excerpt

OBJECTIVES: Serum amyloid A1 (SAA1) is a major acute-phase protein that is increasingly used as a reliable predictor of coronary artery disease (CAD). In this study we aim to screen the SAAI promoter and exons for genetic variants and to determine their association with CAD. In addition, we also...

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Source

Identifiers

PMID: 23357645
DOI: 10.1016/j.atherosclerosis.2013.01.003

Genes

CAD
SAA1
SERPINB2
TNF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23357645-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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