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Article

Apolipoprotein A-I induced amyloidosis.

FEBS letters - 3 Jul 1998

Genschel J, Haas R, Pröpsting M J, Schmidt H H

Abstract excerpt

Amyloidosis is characterized by extracellular deposits of protein fibrils with a high content of beta-sheets in secondary structure. The protein forms together with proteoglycans amyloid fibrils causing organ damage and serious morbidity. Intact apolipoprotein A-I (apoA-I) is an important protein in lipid metabolism regulating the synthesis and catabolism of high density lipoproteins (HDL). Usually, apoA-I is not...

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PMID: 9688527
DOI: 10.1016/s0014-5793(98)00668-1

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