Article
A novel allelic variant of serum amyloid A, SAA1 gamma: genomic evidence, evolution, frequency, and implication as a risk factor for reactive systemic AA-amyloidosis.
Human molecular genetics - 1 Jun 1995
Baba S, Masago S A, Takahashi T, Kasama T, Sugimura H, Tsugane S, Tsutsui Y, Shirasawa H
Abstract excerpt
Reactive systemic amyloidosis, also called AA-amyloidosis is a rare fatal complication of common chronic inflammatory diseases such as rheumatoid arthritis. It has been proposed that as yet undefined factors other than persistent elevation of serum level of the precursor protein, serum amyloid A...
Topics
- Adult
- Aged
- Alleles
- Amyloidosis
- Base Sequence
- Biological Evolution
- DNA
- Female
- Gene Frequency
- Genotype
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Polymorphism, Genetic
- Risk Factors
- Serum Amyloid A Protein