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Binding of <i>Pseudomonas aeruginosa</i> AlgZ to Sites Upstream of the <i>algZ</i> Promoter Leads to Repression of Transcription

20 Jun 2005

Abstract excerpt

Mucoid variants of the opportunistic pathogen Pseudomonas aeruginosa produce the exopolysaccharide alginate and colonize the respiratory tracts of cystic fibrosis patients. The genes encoding the alginate biosynthetic enzymes are clustered in a single operon, which is under tight transcriptional control. One essential activator of the alginate operon is AlgZ, a proposed ribbon-helix-helix DNA binding protein that...

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PMID: 15968052
DOI: 10.1128/jb.187.13.4430-4443.2005

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Binding of <i>Pseudomonas aeruginosa</i> AlgZ to Sites Upstream of the <i>algZ</i> Promoter Leads to Repression of TranscriptionPMID 15968052Read ↗

Pseudomonas aeruginosa AlgZ, a ribbon-helix-helix DNA-binding protein, is essential for alginate synthesis and algD transcriptional activation.Semantic proximity Read ↗

Identification of the algZ gene upstream of the response regulator algR and its participation in control of alginate production in Pseudomonas aeruginosa.Semantic proximity Read ↗

Evidence that the <i>algI</i> / <i>algJ</i> Gene Cassette, Required for O Acetylation of <i>Pseudomonas aeruginosa</i> Alginate, Evolved by Lateral Gene TransferSemantic proximity Read ↗

Identification and characterization of AlgZ, an AlgT-dependent DNA-binding protein required for Pseudomonas aeruginosa algD transcription.Semantic proximity Read ↗

The Pseudomonas aeruginosa homeostasis enzyme AlgL clears the periplasmic space of accumulated alginate during polymer biosynthesisSemantic proximity Read ↗

Mutant Analysis and Cellular Localization of the AlgI, AlgJ, and AlgF Proteins Required for O Acetylation of Alginate in <i>Pseudomonas aeruginosa</i>Semantic proximity Read ↗

Genetic analysis of the alginate biosynthetic gene cluster of <i>Pseudomonas aeruginosa</i> shows evidence of an operonic structureSemantic proximity Read ↗

AlgX Is a Periplasmic Protein Required for Alginate Biosynthesis in <i>Pseudomonas aeruginosa</i>Semantic proximity Read ↗

Identification of <i>Pseudomonas aeruginosa</i> genetic determinants that connect redox metabolism to alginate biosynthesisSemantic proximity Read ↗

Analysis of promoters controlled by the putative sigma factor AlgU regulating conversion to mucoidy in Pseudomonas aeruginosa: relationship to sigma E and stress response.Semantic proximity Read ↗

AmrZ modulates Pseudomonas aeruginosa biofilm architecture by directly repressing transcription of the psl operon.Semantic proximity Read ↗

Pseudomonas aeruginosa AmrZ Binds to Four Sites in the algD Promoter, Inducing DNA-AmrZ Complex Formation and Transcriptional Activation.Semantic proximity Read ↗

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