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Article

Depletion of JARID1B induces cellular senescence in human colorectal cancer

25 Jan 2013

Abstract excerpt

The global incidence of colorectal cancer (CRC) is increasing. Although there are emerging epigenetic factors that contribute to the occurrence, development and metastasis of CRC, the biological significance of epigenetic molecular regulation in different subpopulations such as cancer stem cells remains to be elucidated. In this study, we investigated the functional roles of the H3K4 demethylase, jumonji, AT rich...

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PMID: 23354547
DOI: 10.3892/ijo.2013.1799

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