Article
IL21 and IL21R polymorphisms and their interactive effects on serum IL-21 and IgE levels in patients with chronic hepatitis B virus infection.
Human immunology - 1 May 2013
Li Na, Zhu Qianqian, Li Zhu, Han Qunying, Chen Jinghong, Lv Yi, Wang Yawen, Zeng Xiaoyan, Chen Yanping, Yang Cuiling, Liu Zhengwen
Abstract excerpt
Interleukin (IL)-21 may affect both T-cell and B-cell responses and was suggested to be involved in response to HBV infection. This study explored IL21rs907715 and rs2221903 and IL21R T-83C and rs3093301 polymorphisms and serum IL-21 and IgE levels in 395 patients with chronic HBV infection, 75 HBV infection resolvers and 174 healthy controls. IL21R T-83C was not polymorphic in the study populations. IL21...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.