Article
IL17A gene polymorphisms, serum IL-17A and IgE levels, and hepatocellular carcinoma risk in patients with chronic hepatitis B virus infection.
Molecular carcinogenesis - 1 Jun 2014
Li Na, Zhu Qianqian, Li Zhu, Han Qunying, Zhang Guoyu, Chen Jinghong, Lv Yi, Xing Fanfan, Chen Yanping, Zeng Xiaoyan, Liu Zhengwen
Abstract excerpt
Interleukin (IL)-17A plays important roles in hepatitis B virus (HBV)-induced liver diseases. This study aims to investigate IL17A single nucleotide polymorphisms (SNPs) and the predispositions to chronic HBV infection and hepatocellular carcinoma (HCC) risk and the correlations to IL-17A and IgE levels. Three hundred ninety-five chronic HBV patients, 75 HBV infection resolvers, and 174 healthy controls were...
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