Article
Within-patient emergence of the influenza A(H1N1)pdm09 HA1 222G variant and clear association with severe disease, Norway.
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin - 17 Jan 2013
Rykkvin R, Kilander A, Dudman S G, Hungnes O
Abstract excerpt
The association between a particular mutation in the HA1 subunit of the influenza virus haemagglutinin, D222G, and severe and fatal disease in cases of influenza A(H1N1)pdm09 in Norway during the 2009 pandemic was investigated using pyrosequencing. The prevalence of the variant among fatal cases was 8/26 and among severe non-fatal cases 5/52. No D222G mutations were found among the 381 mild cases. This difference...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.