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Article

Substitutions in position 222 of haemagglutinin of pandemic influenza A (H1N1) 2009 viruses in Spain.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 May 2011

Ledesma Juan, Pozo Francisco, Pérez Ruiz Mercedes, Navarro Jose María, Piñeiro Luis, Montes Milagros, Pérez Castro Sonia, Suárez Fernández Jonathan, García Costa Juan, Fernández Mirian, Galán Juan Carlos, Cuevas María Teresa, Casas Inmaculada, Pérez Breña Pilar

Abstract excerpt

BACKGROUND: A change of aspartic acid (D) to glycine (G) at position 222 in the haemagglutinin (HA) protein of pandemic influenza A (H1N1) 2009 viruses was described in Norway on November 2009 with considerable frequency in fatal and severe cases. This change was detected in other countries and was related only with severe disease. Other substitutions to glutamic acid (E) or asparagine (N) at position 222 were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21353628
DOI: 10.1016/j.jcv.2011.01.020

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