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Article

Three-dimensional culture model to distinguish normal from malignant human bronchial epithelial cells.

The European respiratory journal - 1 Nov 2013

Fessart Delphine, Begueret Hugues, Delom Frederic

Abstract excerpt

In the present study, we have developed an in vitro three-dimensional model to differentiate normal lung cells from lung cancer cells in order to study the mechanisms resulting in lung cancer. Using a reconstituted laminin-rich basement membrane (Matrigel), we were able to culture normal human bronchial epithelial cells and a subset of malignant cells. The two cell types can be readily distinguished by the...

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Identifiers

PMID: 23349442
DOI: 10.1183/09031936.00118812

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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